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| PHERAstar FS ~ Best Performance for all HTS Assays |
The PHERAstar FS is the next generation High-Throughput Screening microplate reader from BMG LABTECH. Built upon the successful PHERAstar Plus platform, the PHERAstar FS has new and unique features that make it superior to any other microplate reader currently on the market. German engineering with the latest technology makes the PHERAstar FS the Gold Standard for HTS.
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| It performs all the leading non-isotopic detection technologies such as: |
 | Ultra-fast UV / Vis Absorbance Spectra |
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| Fluorescence Intensity, including FRET |
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| Fluorescence Polarization |
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| Time-Resolved Fluorescence, including TR-FRET |
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| High-end AlphaScreen® |
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| Luminescence, including BRET |
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Sequential Dual Excitation, Simultaneous Dual Emission and ratiometric calculations are just some of the key features of the PHERAstar FS for multichromatic applications such as FRET, TR-FRET, BRET and FP.
Application specific Optic Modules can be activated by a simple mouse click, and all the necessary components are selected automatically. Assay flexibility is enhanced by top / bottom reading, on-board reagent injectors, precise temperature control and multimode shaking capabilities. The PHERAstar FS provides uncompromised sensitivity, speed and dynamic range in plate formats up to 3456.
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| PHERAstar Plus — The Flagship for HTS |
Based on the highly successful microplate reader PHERAstar, the PHERAstar Plus offers full modularity in all modes and features Advanced HTRF® / TR-FRET, Advanced Luminescence and Advanced Fluorescence Polarization reading modes by integrating the latest technological advancements in optics and electronics. The PHERAstar Plus is the premier multidetection HTS microplate reader with Simultaneous Dual Emission (SDE) detection in all modes. No matter what reading technology you use in your laboratory, the PHERAstar Plus will provide you with the best sensitivity and the fastest reading speed on the market.
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The compact and versatile PHERAstar Plus microplate reader is able to perform all leading non-isotopic detection technologies including:
• Fluorescence Intensity - including FRET
• Fluorescence Polarization - including FarRed™ and Transcreener™
• Time-Resolved Fluorescence - including DELFIA™
• TR-FRET - including HTRF®, LanthaScreen™, LANCE™
• Laser-based AlphaScreen®
• Luminescence
• Absorbance UV/Vis
The PHERAstar Plus is the ONLY microplate reader on the market with four photomultiplier tubes (PMTs) optimized and automatically selected for specific reading modes. This ensures that your assay is read with highest sensitivity, a feature that no other microplate reader offers.
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| FLUOstar Omega |
 | Multidetection microplate reader with four detection modes including a spectrometer.
This new multi-detection microplate reader for life science laboratories features high speed full spectrum absorbance, as well as three additional detection modes including fluorescence intensity, time-resolved fluorescence, and high-performance luminescence for 6-384-well plates. On-board reagent injectors with individually adjustable delivery volumes for each well can be used to initiate kinetic events.
Top and bottom plate reading, 1536 well plate capability for Abs and 384 format for fluorescence measurements, precise temperature control up to 60°C, shaking and well scanning enhance the assay flexibility.
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| FLUOstar OPTIMA |
FLUOstar OPTIMA - Four Measurement Principles for the Widest Range of Applications
The FLUOstar OPTIMA is a fully automated microplate based multi-detection plate reader designed for life science laboratories in academia and industry. The FLUOstar incorporates four different measurement principles:
• Fluorescence Intensity - including FRET and multilable applications
• Time-Resolved Fluorescence - including DELFIA™
• High-Performance Luminescence (flash and glow) - dedicated luminescence circuit
• Absorbance - UV/Vis with 1 cm path length correction |  |
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| POLARstar Omega |
| Multidetection microplate reader with five detection modes including a spectrometer. The POLARstar Omega has all the features of the FLUOstar Omega, plus fluorescence polarization (FP) and simultaneous dual emission. The instrument has two photomultiplier tubes offering simultaneous detection of both channels in FP, FRET and BRET assays for a fantastic speed and accuracy advantage. |  |
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| POLARstar OPTIMA |
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 | Five Measurement Principles in One Reader
POLARstar OPTIMA the multi-detection microplate reader for life science laboratories offers the following five detection modes:
• Fluorescence Polarization
• Fluorescence Intensity - including FRET
• Time-Resolved Fluorescence - including DELFIA™
• High-Performance Luminescence (flash and glow) - including BRET
• Absorbance - UV/Vis with 1 cm path length correction
The POLARstar has all the features of the FLUOstar OPTIMA, plus fluorescence polarization and another very distinctive feature - the POLARstar has two emission photomultiplier tubes (PMTs), which gives the POLARstar a unique advantage because it can read two emission wavelengths simultaneously up to 50 measurement points per second on both channels.
Because the POLARstar does not have to switch filters or polarizers to read the second channel its Simultaneous Dual Emission (SDE) makes FP, FRET, and BRET assays faster and more precise.
Single channel FP readers must essentially read the microplate twice - once for parallel emission and once again for perpendicular emission. But the POLARstar collects both emission vectors simultaneously for a fantastic speed advantage. The same is true for FRET or BRET experiments that have two or more emission wavelengths. |
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| SPECTROstar Omega |
SPECTROstar Omega
Microplate based spectrometer
The new SPECTROstar Omega is capable measuring at fixed user-defined wavelengths or of capturing a full absorbance spectrum (220-850 nm) in less than 1 second per well, at a resolution of 1 nm. Due to the modular concept of the Omega reader family the SPECTROstar Omega is entirely upgradeable to a FLUOstar or POLARstar Omega with four or five detection modes, respectively
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| LUMIstar Omega |
 | Microplate based luminometer. The LUMIstar Omega is a compact and modular microplate luminescence reader that is designed for the widest possible range of applications based on luminescence labels. The instrument features a built-in filter wheel for measurement at distinct wavelengths, on-board reagent injectors, precise temperature control up to 60 °C, and is upgradeable to FLUOstar or POLARstar Omega, with full absorbance spectrum and four or five detection modes, respectively. |
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| LUMIstar OPTIMA |
The Fully Upgradeable Luminometer for Measuring Flash and Glow Luminescence
The LUMIstar OPTIMA is a fully automated microplate-based luminometer that is designed for the widest possible range of applications based on luminescence labels:
• Reporter gene assays luciferase, ß-galactosidase, gene activities with luminescence substrates (e.g. luminol, acridinium esters, dioxetanes, etc.)
• Luminescent Immunoassays
• Cell-based assays (e.g. cytotoxity and proliferation, intracellular Ca2+ with aequorin)
• ATP assays
• GUS assays (ß-glucuronidase)
• ROS (reactive oxygen species)
• Enzyme activity assays
• Nucleic acid detection (PCR Quantification)
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| RUBYstar |
 | The Gold Standard Microplate Reader for HTRF® measurements
The RUBYstar is the best performing HTRF® reader available. The unit features a nitrogen laser at 337 nm and dual-read head for simultaneous detection at 620 nm and 665 nm making it the fastest and most sensitive reader for Cisbio's HTRF® assays.
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| NOVOstar |
Liquid Handling Combination for Cell Based Assays
Designed for cell-based assays and a whole lot more, the NOVOstar provides both fluorescence and luminescence measurements in addition to the flexibility of an on-board reagent pipet. The pipet can transfer reagents from plate to plate or from three reagent stations to the measurement microplate. Other unique NOVOstar features include multiple kinetic windows allowing you to collect high-resolution data when you need it and high-performance luminescence for extraordinary sensitivity in cellular assays
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| NEPHELOstar |
 | Laser based light scatter measurement in microplates
The NEPHELOstar measures forward light scatter in microplates and offers the HTS/ Drug Screening laboratory an easy to use, low cost, and rapid method for checking the solubility of compounds. The flexibility and performance of the NEPHELOstar allows more applications to be adapted to nephelometry than ever before:
• Drug solubility testing
• Bacterial and fungal growth
• Quality control
• Quantification of macromolecules (e.g. specific proteins)
• Formation of immunocomplexes to name but a few
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| SPECTROstar Nano |
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 | The SPECTROstar Nano represents a revolution in absorbance measurement instrumentation with the flexibility to perform assays quickly and easily in both microplates or via the built-in cuvette port.
Using a spectrometer, this new absorbance microplate reader captures a full UV-Visible spectrum (220 to 1000 nm) in less than 1 sec/well and measures sample volumes down to 2 µL.
The speed of the spectrometer, simple push button operation, and the capacity to design and save individual assay protocols give users an unmatched flexibility to optimize settings for all absorbance experiments.
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| The SPECTROstar Nano also includes the following outstanding features |
 | Ultra-fast UV/Vis absorbance spectrometer |
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| Captures a spectrum from 220 to 1000 nm in less than 1 s/well |
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| Selectable spectral resolution of 1 - 10 nm |
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| 6- to 1536-well microplate format compatibility |
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| Low volume 2 µL measurements for DNA, RNA, protein, etc. |
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| Standard cuvette port for individual samples |
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| Incubation up to 45°C for microplate and cuvette |
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| Gas vent for atmospheric sensitive samples |
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| Well scanning, kinetic and endpoint measurements |
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| Multimode plate shaking capabilities |
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| Assay specific quick run protocols |
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| Powerful Data Analysis Software - MARS |
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| FDA 21 CFR part 11 compliant |
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| Robot compatibility
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| Atmospheric Control Unit (ACU) |
 | BMG LABTECH now offers the Atmospheric Control Unit (ACU) - a complete solution for fully regulated independent control of both oxygen (O2) and carbon dioxide (CO2) levels within your multimode microplate reader.
Available for the entire range of Omega microplate readers, the microprocessor controlled ACU offers dual independent control of both gases within the microplate reading chamber. The microprocessor controlled unit can regulate CO2 (0 - 20%) and O2 (1 - 19%) independently, making it unnecessary to change gas cylinders or piped gas supplies to reproduce certain physiological conditions needed for cell-based assays. |
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When used in combination with the Omega's other features such as extended temperature control up to 65°C and shaking (orbital, double orbital and linear), users can reproduce most physiological conditions making cell-based assays more biologically relevant. The Omega series of microplate readers can measure multiple detection modes including Fluorescence Polarization (FP), Fluorescence Intensity, Time-Resolved Fluorescence (TRF), TR-FRET, AlphaTechnologies®, High-Performance Luminescence and UV/Vis spectrometer based absorbance. Applications can be run in a dedicated mode or a combination of all modes to acquire all the data you need in a single experiment. The multimode capabilities, together with the Atmospheric Control Unit , are especially advantageous for a variety of applications including Mammalian Cell Assays, Stem Cell Assays, Hypoxia, Cell Viability, Cell Proliferation, Migration Studies, Invasion Assays, Intracellular pH, Angiogenesis, Ischemia / Reperfusion, and many more. Incorporating the ACU into an Omega microplate reader, extended cell based experiments can now even be performed without user intervention, providing a true walk away assay solution.
This makes the BMG LABTECH ACU the most flexible gas control system available in a microplate reader. |
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| Stacker |
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BMG LABTECH´s Flexible Microplate Handling System for Rapid Mid-Throughput
The Stacker is designed for integration with BMG LABTECH´s microplate readers minimizing microplate handling. It provides loading, unloading, restacking and continous feeding of up to 50 microplates. It is also possible to read single plates without using the magazines.
Software package
The Stacker Control software operates the Stacker / reader combination: the Stacker is controlled via a serial interface and the reader is controlled via a DDE interface to the reader control program. The definition of the measurement protocol as well as the configuration of the reader is done by using the reader control software. In the Stacker control software you define the batch operation, e.g. the test name and number of plates.
User defined run scripts
Script mode allows users to write their own run scripts, which give the user unlimited flexibility. This function can be used to choose different test definitions for different plates in one batch run or to perform more than one measurement on one plate.
Barcode Reader
The Stacker is designed to read barcodes from several positions on the microplate.
The Stacker accomodates all types of microplate formats. |  |
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| THERMOstar |
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| THERMOstar - Intelligent Microplate Incubation |
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The THERMOstar is a high performance microplate incubator and orbital shaker which accommodates up to four microplates. The THERMOstar can be used for any enzyme or cell-based assays requiring uniform and strictly controlled incubation up to 56°C and effective mixing.
Temperature, shaking speed, and incubation time are fully programmable via the keypad, while the status parameters are displayed on the LCD in real time via an easy to use interface.
Microprocessor controlled heating plates above and below the microplates provide uniform temperature with less than 1.0°C variation between any two wells. This ensures outstanding and repeatable assay performance.
Features:
• Heating plates above and below the microplates
• User definable parameters - temperature, RPM, and time
• Shakes and incubates four microplates simultaneously
• Incubation up to 56°C in 1°C steps
• Excellent temperature accuracy and uniformity across the plate
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