Check out our latest Research & Biotech promotions and events

All-Ireland Chromatin Consortium

The All Ireland Chromatin Consortium has run an annual one-day meeting to bring together chromatin researchers from across the island of Ireland since 2022.

The All-Ireland Chromatin Consortium  (AICC) is a network of researchers on the Island of Ireland who are linked by interests to investigating all aspects of chromatin mechanisms in disease.

The aims of the AICC are to promote scientific exchange across Ireland and beyond, to foster collaborations between labs, to expand expertise in the area of chromatin biology, and to raise the visibility of Irish chromatin research.

The AICC hosts inspiring webinars by leading international and emerging researchers, and holds an annual conference as an active and dynamic forum for PhD students and Postdocs working on chromatin biology to present and discuss their work and gain state of the art knowledge. 

Date & Time Wed. May 27, 2026
Location Conway Institute, UCD
Register to talk or poster Thu. April 16, 2026
Register to attend Wed. May 20th
Cost Registration including lunch is FREE

 

Other Upcoming Events & Exhibitions

 

Date Title Location
22 May Cancer Research Centre First-Year PhD Symposium Queen’s University
26 May Coffee Morning with CST DCU
26 June All-Ireland RNA Club Meeting UCD
CST antibodies

Maximize Your Budget with 20% Off T-Size Antibodies and Sampler Kits

Trial Without the Error

Why commit to a large vial when you’re testing new ground?

These 20 μL sizes allow you to integrate more antibodies into your current protocols, giving you the freedom to screen multiple targets and run additional pilot studies with ease.

Get more value from your budget with 20% off T-size formats—backed by the trusted reliability of CST.

  • Include more targets in your experiment
  • Get 20% off your next order
  • Use code EU26TS20

Terms and Conditions: 20% discount off regularly priced trial size products and sampler kits for eligible locations. Eligible locations: Africa, Bulgaria, Croatia, Czech Republic, Denmark, Egypt, Estonia, Finland, Greece, Hungary, Ireland, Israel, Italy, Latvia, Lithuania, Middle East, Norway, Poland, Portugal, Romania, Serbia, Slovakia, Slovenia, South Africa, Spain, Sweden, Switzerland, and Turkey. No cash or cash equivalent and cannot be sold or otherwise bartered. No substitutions. Offer valid on new catalog orders only, restrictions apply. Offer may not be applied to existing, pending or prior orders, ineligible items, taxes, or shipping and handling charges. Returns of any portion of the purchase will require equal forfeiture of offer or amount equal to offer. Promotion code: EU26TS20 must be referenced when placing an order. All other products/services including but not limited to PTMScan® Services, kits, “BSA and Azide Free” antibodies, GMP-grade reagents, SignalStar™ Multiplex IHC  products and custom orders are excluded. Cannot be combined with any other promotions or discounts. Void if copied or transferred, where prohibited by law or otherwise restricted. Offer Expires: June 16, 2026. Cell Signaling Technology (together with its subsidiaries, “CST”) retains the right to modify or stop the promotion at any time without notice.

White lab bottle with a blue screw cap and the Cell Signaling Technology logo on the label.

Exclusive 30% Discount* on Monarch Nucleic Acid Purification kits and Luna (RT-)qPCR mixes’

Choose Monarch for uncompromising quality of your nucleic acid purification

Monarch nucleic acid purification kits provide fast and reliable isolation and purification of high quality DNA and RNA from a variety of sample types. Technologies used include best-in-class silica columns, silica‑coated mag beads, or glass‑beads for the isolation of high molecular weight DNA. The resulting nucleic acids are highly pure and ready for sequencing, cloning, PCR, and other enzymatic applications.

The Monarch nucleic acid purification portfolio can serve your needs, whether you are isolating nucleic acids from biological samples, cleaning up DNA and RNA from enzymatic reactions, extracting DNA fragments from gels, or purifying plasmids.

Monarch DNA and RNA kits use purposefully reduced‑plastic columns and bottles and come in compact packaging, providing environmental responsibility without compromising on performance.

Optimize your (RT-)qPCR with Luna

  • Convenient master mix and supermix formats and user-friendly protocols simplify reaction setup.
  • Non-interfering, visible tracking dye eliminates pipetting errors.
  • Formulated with a unique passive reference dye, compatible across a wide variety of thermal cyclers.
  • Luna WarmStart RT paired with Hot Start Taq enables room temperature setup and stability.
  • 4X option allows for more sample input, increasing sensitivity.
  • Available in a lyophilized format.
  • Offer valid from April 1st, 2026 to June 30th, 2026
  • Use promo code LUMO2026 when ordering
  • *30% discount on the catalogue price

Webinars and Training

Redefining Single-Cell Analysis: Comprehensive Intracellular Protein Profiling with InTraSeq Technology

May 28, 2026

Are you looking to capture the full picture of cellular signaling and gene expression at the single-cell level? Traditional single-cell sequencing often focuses on whole-cell transcripts or surface markers, missing the crucial intracellular dynamics orchestrated by proteins and their modifications.

This seminar focuses on InTraSeqTM Single Cell Analysis (Intracellular Protein and Transcriptomic Sequencing), a technology from CST that allows for the simultaneous detection of both RNA transcripts and intracellular proteins (including transcription factors and PTMs) from the same single cell.

Attend this session to understand the mechanics of InTraSeq Technology, see how its ability to integrate protein state (like phosphorylation) with gene expression within individual cells unlocks unprecedented insights into signaling heterogeneity, and learn how to leverage this technology to push the boundaries of single-cell biology.

Presented by: Yannick Nossin, PhD Field Application Scientist at CST

CUT&Tag Just Got More Reliable with Drosophila Spike-in Controls

CUT&Tag with Normalization

The Cleavage Under Targets & Tagmentation (CUT&Tag) is a faster, more cost-friendly alternative to ChIP-seq that utilizes a primary antibody, secondary antibody and pAG-Tn5 to identify protein-DNA interactions across the genome.

Cell Signaling Technology (CST) has expanded our CUT&Tag portfolio to include two
NEW! CUT&Tag Drosophila spike-in normalization control kits to account for any
technical variability that might occur during your assay–from cell handling through
sequencing.

Enjoy the Benefits of CUT&Tag

Faster time to results 1-2 days from cells to DNA library. CUT&Tag
is 25% quicker than CUT&RUN due to
streamlined library prep
Low sample requirement ~40x less sample than ChIP-Seq
Low sequencing depth =
sequencing cost savings
Only ~2 million high-quality reads are
required due to low background
In vivo method Assays are performed using native chromatin,
eliminating cross-linking artifacts

Streamlined DNA Library Prep

Schematic of a spike-in ATAC-like workflow: experimental cells and Drosophila spike-in nuclei receive antibody tagging (primary/secondary Ab, H2Av mAb) on concanavalin A beads, followed by Mg2+-activated Tn5 tagmentation, cell lysis and DNA release, DNA purification, amplification and NGS, then normalization of sequencing signals using the Drosophila spike-in.

CUT&Tag cuts out the in vitro adaptor ligation step, allowing you to move directly to
PCR amplification of your library, making it 25% faster than CUT&RUN. You can also
choose to add a Drosophila spike-in normalization control to ensure your data reflectsrelevant biological changes.

When to Use CUT&Tag vs CUT&RUN

Both CUT&Tag and CUT&RUN help you unravel protein-DNA interactions when you are short on time and/or sample. Use the table below to figure out which method is the right one for you.

  CUT&Tag CUT&RUN
Compatible with Histones Yes Yes
Compatible with Transcription Factors Depends Yes
Compatible with Cofactors Depends  Yes
Compatible with Drosophila Spike-in Controls Yes  Yes
Compatible with Yeast Spike-in Controls No  Yes
Compatible with qPCR No  Yes
Compatible with NG-seq Yes  Yes
DNA Library Prep In vivo In vitro
Cells to DNA Library 1-2 days 2-3 days
Low Cell Yes Yes
Single Cell Amenable Yes No
Sequencing Depth 2M 3-5M

Use CST® Normalization Controls to Increase Confidence in CUT&Tag Data

CST CUT&Tag kits, reagents, and controls are validated together with the same rigor applied to all of our products to ensure performance. You’ll get the reliability required to generate data you can trust every time.

Two-panel chart comparing sequencing signals: 'Before Normalization' top and 'After Normalization' bottom, showing peaks across HOXA gene region (HOXA1, HOXA2, HOXA3, HOXA-AS3, HOXA9) with positions around 27,090–27,170 kb; blue/green traces where peaks indicate signal intensity.

New Products This Month from NEB!

Developed in collaboration with Touchlight, NEB’s EnClose Cell-free dbDNA Synthesis Kit includes everything needed to enzymatically generate closed-ended linear double-stranded DNA called doggybone or dbDNA. The robust combination of phi29-XT DNA Polymerase for high-yield rolling circle amplification (RCA) and EnClose TelN Protelomerase for deconcatenation and covalent closure of linear dsDNA ends enables a streamlined one-day workflow that produces cell-free dbDNA for downstream applications such as in vitro transcription (IVT), lentiviral (LV) and adeno-associated virus (AAV) payloads and more.

EnClose TelN Protelomerase, a telomere resolvase from phage N15, cuts dsDNA at a 56 bp recognition sequence and leaves covalently closed ends at the site of cleavage through hairpin formation. EnClose TelN Protelomerase (M0768S) replaces the previous TelN Protelomerase (M0651S), which was originally released as an Enzyme for Innovation (EFI) and will be discontinued. The updated EnClose TelN Protelomerase differs from the EFI version in that it retains an N‑terminal His tag, allowing users to verify protein clearance after covalently closed DNA ends are formed.

Latest Blog

Choosing the right cell detachment method for adherent cells: What you need to know

Cell detachment is a critical step in cell culture workflows using adherent cells. If you choose the wrong reagent or leave it on too long, you can damage your cells. Selecting the right cell detachment method directly affects cell viability and downstream results.

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