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All-Ireland Chromatin Consortium

The All Ireland Chromatin Consortium has run an annual one-day meeting to bring together chromatin researchers from across the island of Ireland since 2022.

The All-Ireland Chromatin Consortium  (AICC) is a network of researchers on the Island of Ireland who are linked by interests to investigating all aspects of chromatin mechanisms in disease.

The aims of the AICC are to promote scientific exchange across Ireland and beyond, to foster collaborations between labs, to expand expertise in the area of chromatin biology, and to raise the visibility of Irish chromatin research.

The AICC hosts inspiring webinars by leading international and emerging researchers, and holds an annual conference as an active and dynamic forum for PhD students and Postdocs working on chromatin biology to present and discuss their work and gain state of the art knowledge. 

Date & Time Wed. May 27, 2026
Location Conway Institute, UCD
Register to talk or poster Thu. April 16, 2026
Register to attend Wed. May 20th
Cost Registration including lunch is FREE

 

Exclusive 30% Discount* on Monarch DNA kits and Luna Mixes

Choose Monarch for uncompromising quality of your nucleic acid purification

Monarch nucleic acid purification kits provide fast and reliable isolation and purification of high quality DNA and RNA from a variety of sample types. Technologies used include best-in-class silica columns, silica‑coated mag beads, or glass‑beads for the isolation of high molecular weight DNA. The resulting nucleic acids are highly pure and ready for sequencing, cloning, PCR, and other enzymatic applications.

The Monarch nucleic acid purification portfolio can serve your needs, whether you are isolating nucleic acids from biological samples, cleaning up DNA and RNA from enzymatic reactions, extracting DNA fragments from gels, or purifying plasmids.

Monarch DNA and RNA kits use purposefully reduced‑plastic columns and bottles and come in compact packaging, providing environmental responsibility without compromising on performance.

Optimize your (RT-)qPCR with Luna

  • Convenient master mix and supermix formats and user-friendly protocols simplify reaction setup.
  • Non-interfering, visible tracking dye eliminates pipetting errors.
  • Formulated with a unique passive reference dye, compatible across a wide variety of thermal cyclers.
  • Luna WarmStart RT paired with Hot Start Taq enables room temperature setup and stability.
  • 4X option allows for more sample input, increasing sensitivity.
  • Available in a lyophilized format.
  • Offer valid from April 1st, 2026 to June 30th, 2026
  • Use promo code LUMO2026 when ordering
  • *30% discount on the catalogue price

Webinars and Training

Accelerating Epigenomic Discovery: Chromatin Profiling Through CUT&RUN and CUT&Tag

April 23, 2026

Have you heard of CUT&RUN and CUT&Tag? These next-generation chromatin profiling technologies enable high-resolution mapping of DNA-binding proteins, histone modifications, and chromatin accessibility with exceptional sensitivity and low input requirements. In this seminar, you will learn how CUT&RUN and CUT&Tag work, the distinct advantages each method offers, and the key experimental considerations that guide the choice between them.

Join us to deepen your understanding of these powerful enzymatic profiling approaches and discover how they can help you unravel complex epigenetic regulation and accelerate your own scientific discoveries.

Presented by: Christina Theisgen, PhD Sr. Global Trainer at CST

Redefining Single-Cell Analysis: Comprehensive Intracellular Protein Profiling with InTraSeq Technology

May 28, 2026

Are you looking to capture the full picture of cellular signaling and gene expression at the single-cell level? Traditional single-cell sequencing often focuses on whole-cell transcripts or surface markers, missing the crucial intracellular dynamics orchestrated by proteins and their modifications.

This seminar focuses on InTraSeqTM Single Cell Analysis (Intracellular Protein and Transcriptomic Sequencing), a technology from CST that allows for the simultaneous detection of both RNA transcripts and intracellular proteins (including transcription factors and PTMs) from the same single cell.

Attend this session to understand the mechanics of InTraSeq Technology, see how its ability to integrate protein state (like phosphorylation) with gene expression within individual cells unlocks unprecedented insights into signaling heterogeneity, and learn how to leverage this technology to push the boundaries of single-cell biology.

Presented by: Yannick Nossin, PhD Field Application Scientist at CST

Latest Blog

CD34+ progenitor cells: From blood production to immunity

CD34⁺ hematopoietic progenitor cells (HPCs) are the proliferative intermediates that drive day-to-day renewal of the blood and immune cells. Arising from hematopoietic stem cells, HPCs have limited self-renewal but a robust capacity to expand and differentiate into lineage-restricted myeloid and lymphoid progeny. Read on to learn about the role of CD34⁺ HPCs and other CD34+ populations and how to expand them.

New Products this month from CST!

Rad51 (F4L4Y) Rabbit Monoclonal
Antibody #84555

IHC-P: IHC analysis of paraffin-embedded human esophageal carcinoma using #84555.

A key protein in DNA double-strand break repair

Cells sense and repair DNA double-strand breaks (DSBs) through two signaling pathways: non-homologous end joining (NHEJ) and homologous recombination (HR). Rad51 regulates HR by polymerizing filaments along single-stranded DNA through interactions with Rad54 and BRCA2. Five Rad51 paralogs (XRCC2, XRCC3, Rad51B, Rad51C, and Rad51D) exist in vertebrates, and all are thought to be required
for efficient HR. RAD51 is overexpressed in over 20 types of cancer and has been associated with reduced overall survival in at least 10 cancers. It is therefore a promising biomarker for various cancers. #84555 is suitable for WB, IP, and IHC-P using human, mouse, rat, and monkey samples.

p21 Waf1/Cip1 (F7S9M) Rabbit Monoclonal Antibody #39375

IHC-P: IHC analysis of paraffin-embedded LL/2 syngeneic tumor using #39375.

Tumor suppressor protein p21 Waf1/Cip1

p21 Waf1/Cip1 acts as an inhibitor of cell cycle progression, primarily downstream of the tumor suppressor protein p53. By colocalizing with the CDK2 complex, it inhibits kinase activity and blocks G1/S phase progression. In particular, it is involved in cell cycle arrest upon DNA damage, induction of cellular senescence, promotion of differentia tion, and suppression of apoptosis. Its functions are known to vary depending on its subcellular location. Upon UV-induced DNA damage or during cell cycle stages when cdc2/cyclin B or CDK2/cyclin A are activated, p53 is phosphorylated and positively regulates p21 transcription via p53 response elements. Meanwhile, p21 protein levels arenegatively regulated by ubiquitination and proteasomal degradation.#39375 is suitable for WB, IP, and IHC-P using mouse samples.

New Products This Month from NEB!

Fragmenting genomic DNA (gDNA) is key to improving long-read sequencing performance and data yield. NEBNext UltraShear® Long Read is a fast, flexible enzymatic method for gDNA fragmentation, designed for use upstream of Oxford Nanopore Technologies® (ONT) and PacBio® library preparation and sequencing. This time-tunable solution allows precise fragment sizing from 2 kb to 30 kb in as little as 30 minutes, while preserving native methylation marks. It works with a broad input range (250 ng–5 µg) and is compatible with automation, making it easy to scale as sequencing needs grow. NEBNext UltraShear Long Read provides a cost-effective and reliable alternative to mechanical shearing methods.

For Research Use Only. Not for use in diagnostic procedures.

  • Magnetic bead-based extraction for efficient and reproducible isolation of circulating cell-free DNA (cfDNA) from biofluids.
  • Recover cell-free DNA in the typical size range (150-300 bp), and as low as 50 bp.
  • Obtain consistent results for sample types with challenging biological variability.
  • Available in 20-prep or 100-prep formats for 2 ml samples and scalable to accommodate 1-4 ml sample inputs.
  • Elute in low elution volumes without the need for additional concentration steps that lead to yield loss.
  • Achieve streamlined sample-to-result workflows by integrating with NEB’s sequencing and amplification solutions.

Supercoiled Extend DNA Ladder enables accurate sizing of a wide range of supercoiled DNA, including supercoiled plasmids up to 15 kb, and has a convenient reference band at 6 kb.

  • Supercoiled DNA molecular weight marker
  • Size range: 2 to 15 kb
  • Convenient reference band at 6 kb
  • Supplied with a vial of Gel Loading Dye, Purple (6X), no SDS (NEB #B7025)
  • Suitable for 100 gel lanes

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